The 7-deaza-dGTP provided in the form of a 10 mM standard solution is essentially an "engineered-defined" reaction input unit, offering clear and direct value in scientific research systems:

✅ Simplified Operation Workflow
Ready-to-use solution eliminates preparation steps, shortens experimental setup time, reduces human error, and improves experimental efficiency.

✅ High Reproducibility
Maintains a uniform physical form across different batches and experiments, enhancing the reliability of scientific data.

✅ System Construction Friendly
More suitable as a reaction module for embedding into standard processes such as PCR, amplification, and sequencing.

✅ Standardized Input Variable
Clear concentration and stable state facilitate the establishment of reproducible and citable reaction parameter systems.

Chinese Name: 7-Deaza-2′-deoxyguanosine 5′-triphosphate, Lithium salt

English Name: 7-Deaza-2'-deoxyguanosine-5'-triphosphate, Sodium salt

Abbreviation: 7-deaza-dGTP

CAS Number: 101515-08-6

Molecular Formula: C11H17N4O13P3

Molecular Weight: 506.19

Specifications: 25 ul / 100 ul / 250 ul (Custom packaging supported)

Form: Solution

Concentration: 10mM

Cat. No.: G09020008

Stock Status: In Stock

· High GC Template PCR Amplification
Used in combination with DMSO and betaine, it effectively overcomes the amplification bottleneck of GC-rich DNA sequences and improves product specificity.

· Telomerase Activity Inhibition Research
Competitively incorporates into telomeres and alters their secondary structure, blocking telomerase recognition and synthesis.

· RT-qPCR Compatibility Study
Evaluates its impact on cell lysis, RNA stability, and downstream reverse transcription.

The core value of 7-deaza-dGTP stems from its precise molecular design. It replaces the nitrogen atom at position 7 of the guanine base, which is prone to forming strong hydrogen bonds, with a carbon atom. This key modification effectively inhibits the formation of Hoogsteen hydrogen bonds, thereby significantly reducing the formation of complex secondary structures (such as G-quadruplexes and hairpin structures) in DNA templates. This allows DNA polymerases to proceed more smoothly when amplifying high GC regions or complex sequences, fundamentally improving PCR amplification efficiency and sequencing quality.

Chinese Name: 7-Deaza-2′-deoxyadenosine 5′-triphosphate, Lithium salt

English Name: 7-Deaza-2'-deoxyadenosine-5'-triphosphate, Sodium salt

Abbreviation: 7-Deaza-dATP

CAS Number: 67460-15-5

Form: Solution

Concentration: 10mM

Cat. No.: G09020009

Stock Status: In Stock